Salvage versus adjuvant radiotherapy after radical prostatectomy: argument for adjuvant radiotherapy
نویسندگان
چکیده
منابع مشابه
Adjuvant and salvage radiotherapy after radical prostatectomy.
BACKGROUND Following radical prostatectomy, between 15 and 60% of all patients with pT3 prostate cancer experience persistence or increasing levels of prostate-specific antigen (PSA) as a sign of tumor persistence or progression within 5 years. Retrospective studies have shown a rate of 35-55% of positive biopsies from the vesicourethral anastomosis in this situation. Best treatment for these d...
متن کاملSalvage radical prostatectomy after radiotherapy.
OBJECTIVES To determine the oncological and functional results obtained after salvage radical prostatectomy (SRP) in patients with recurrence following radiotherapy (3 consecutive PSA rises after a nadir until the year 2006, then 2 ng/mL above nadir ) for prostate cancer (PC), and to analyze the impact of different pre-and postoperative variables on biochemical recurrence-free survival (BCR-fre...
متن کاملAdjuvant and salvage radiotherapy after prostatectomy: AUA/ASTRO Guideline.
PURPOSE The purpose of this guideline is to provide a clinical framework for the use of radiotherapy after radical prostatectomy as adjuvant or salvage therapy. MATERIALS AND METHODS A systematic literature review using the PubMed®, Embase, and Cochrane databases was conducted to identify peer-reviewed publications relevant to the use of radiotherapy after prostatectomy. The review yielded 29...
متن کاملAdjuvant Radiotherapy after Radical Prostatectomy: Indications, Results and Side Effects
advantage has not been demonstrated to date. For patients with positive margins in organ-limited prostate carcinomas (pT2 R1) randomized studies are recommended. It is unclear whether adjuvant radiotherapy is superior to radiotherapy for PSA levels increasing from the undetectable range after radical prostatectomy. To answer this question randomized studies are needed. Copyright © 2007 S. Karge...
متن کاملAdjuvant versus salvage radiotherapy following radical prostatectomy: do the AUA/ASTRO guidelines have all the answers?
Debate continues surrounding the indications for adjuvant and salvage radiotherapy as the published randomized trials have only addressed adjuvant treatment. Salvage radiotherapy has been advocated to limit significant toxicity to patients that would not have benefited from immediate adjuvant radiotherapy. The American Urological Association and American Society for Radiation Oncology guideline...
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ژورنال
عنوان ژورنال: Canadian Urological Association Journal
سال: 2013
ISSN: 1920-1214,1911-6470
DOI: 10.5489/cuaj.1081